Potts was born in Nashville, Tennessee, and grew up in Franklin, Kentucky, where she graduated from Franklin-Simpson High School. She is the daughter of Powell Grisette Potts and Dorothy Harris (Billingslea) Potts and has two older sisters, Mary Eleanor (Potts) Hovious, and Elizabeth Grissette ("Dollie") Potts. She received a Bachelor in Fine Arts degree (in theater arts) from Stephens College in Missouri.
Potts made her debut on the big screen in 1978 on the Metro-Goldwyn-Mayer comedy film Corvette Summer, with Mark Hamill. She was nominated for a Golden Globe Award in 1979 for role in the film. In 1982 she won Genie Awards for Best Performance by a Foreign Actress for role in the film Heartaches, about a young woman, married to a stock car racer and carrying his friend's child.
Potts has starred or appeared in the following:
- Pretty In Pink
- Toy Story
- Toy Story 2
- Ghostbuster III
- Love & War
- Ugly Betty
- Law and Order: Special Victims Unit
- Good Christian Belles
Annie Potts at www.starpulse.com